Precision DNA Fragmentation Made Simple – Lanende NonContact Ultrasonic DNA Shearer

Break through complex molecular biology workflows with our NonContact Ultrasonic DNA Shearer — a highperformance instrument that transforms sample prep for genomics, epigenetics, diagnostics and synthetic biology through controlled, contaminationfree fragmentation .

How It Works

Based on ultrasonic mechanical vibration and cavitation effects, the device converts highfrequency electrical signals into intense acoustic waves inside the sample tube. These create microscopic bubbles that rapidly grow and collapse, producing shockwaves and microjets to precisely shear DNA chains without direct probe contact . This ensures:

· Isothermal processing with optional external chiller connection to protect temperaturesensitive samples.

· Closedtube operation — each sample is processed separately, eliminating crosscontamination and aerosol risks.

Key Features

· 7inch medicalgrade touchscreen — intuitive control of ultrasound time, gap time, power, and alarm temperature .

· Wide frequency range — 20–400 kHz mixedfrequency mode with adaptive tracking for versatile sample types .

· Flexible throughput — handles multiple sample volumes in separate sealed tubes, meeting diverse experimental needs .

· Batterydriven rotating motor — simplifies installation and speeds deployment .

· Realtime temperature monitoring — guards against denaturation during prolonged runs .

· Automatic fault detection & alarms — continuously monitors operational status for safe, stable performance .

Broad Application Coverage

· Genomics: NGS library construction (WGS, WES), metagenomic studies .

· Epigenetics: ChIPseq, ATACseq sample preparation .

· Molecular Diagnostics: FFPE DNA extraction and fragmentation .

· Synthetic Biology: Gene assembly fragment preparation .

· Forensics: Standardization of trace DNA samples .

· Multifield utility: Bacterial cell lysis, protein extraction, spore disruption, emulsification, homogenization, dissolution acceleration, catalysis .

Empowering Efficiency Through Targeted Solutions

Lanende couples this technology with applicationspecific workflows to solve real laboratory challenges :

HighThroughput Sequencing & Library Construction Solution

For gene sequencing companies, clinical labs, hospitals, university genomics facilities.

Delivers isothermal shearing, strict fragment length control, zero aerosol pollution, and excellent data reproducibility aligned with NGS requirements .

Chromatin Immunoprecipitation (ChIP) FullProcess Solution

For epigenetics teams and biopharma R&D groups.

Uses noncontact ultrasound to shear chromatin while maintaining low temperature, preventing activity loss common with traditional probe sonication; ensures fragment size matches antibody binding profiles .

Why Choose Lanende

As a comprehensive experiment instrument manufacturer and solution provider, we integrate IoT technology for remote monitoring, cloud data storage, and intelligent management — helping labs build a “smart detection network” . Our commitment to technology empowers business efficiency means you get not just hardware, but endtoend precision, safety, and scalability for your molecular workflows.

Contact us to configure a DNA shearing solution tailored to your research or diagnostic pipeline.